On the basis of researches about GHS classification and identification of dangerous chemicals, combined with the current practice of inspection and quarantine work, by adopting J2EE technology framework, the dangerous chemicals GHS classification assessment system applying GHS classification database and self built database were established. The overall technical logic architecture of the system consisted of access layer, application layer, support layer and resource layer. The system mainly included the management module of basic data, the module of classification query and identification, the output module of judging results, the management module of self-built testing databases. The application practice showed the system could realize the automation and intelligence of the classification and identification of dangerous chemicals. Meanwhile, it could reduce the workload of inspection and appraisal, decrease the unnecessary loss of repeated testing and evaluation, and enhance the effectiveness of law enforcement.