The internet of things technology is characterized by high intelligence, automation, informatiztion and is widely used in transport packaging industry. Its advantage is mainly embodied in two aspects: intelligent management in the circulation and differentiation according to the characteristics of the packaged contents. According to the problems in existing transport packaging, transport packaging design technology in the context of the internet of things should follow the principles of safety and environmental protection, simplicity and universalization, economic effectiveness and humanistic care. With the methods of analyzing various influencing factors systematically, establishing comprehensive transport packaging design model, with reasonable design concept and testing packages, the effective implementation of information management of the whole process and humanistic care could be realized after fulfilling traditional functions.