In view of a solution of the interference or excessive leakage clearance in the production assembly process of vortex compressors, a method with assembly sequence and Monte Carlo combined has been proposed for assembly tolerance analysis. Firstly, a three-dimensional tolerance analysis software is adopted to establish a tolerance simulation model for the vortex compressor, followed by an assembly tolerance analysis conducted on its leakage clearance, so as to optimize it to the ideal fluctuation range. Subsequently, a comparison is made of the scroll compressor performance before and after tolerance optimization. Finally, comparative experiments are conducted to verify the performance of the optimized scroll compressor. The results show that the experimental results are basically consistent with the research results. Based on a tolerance optimization, the outlet mass flow rate of the scroll compressor increases by 21.8%, the outlet temperature decreases by 7.86%, and the power of the moving scroll shaft increases by 4.16% respectively.