Based on ABAQUS simulation software, a thermal coupling model has thus been established for GH4169 single grain three-dimensional orthogonal grinding. An investigation has been made of the effects of grit morphology, grinding speed, and grinding depth on grinding force and temperature during the grinding process. The simulation results show that the minimum average grinding force experienced by hexahedral grits is 0.14 N; the grinding force and the surface temperature of the workpiece after grinding are positively correlated with the grinding depth and speed; the highest temperature of the workpiece during the grinding process occurs in the second shear zone where shear deformation and frictional work occur; the highest temperature of the grit occurs at the sharp corner of the front cutting edge of the abrasive grain, among which the average unit temperature of the hexahedral grit front cutting edge is the lowest, at 689.9 ℃.