In view of a clarification of the mechanism of safety accidents brought about by typhoons on residential entrance doors, a CFD numerical simulation method has been adopted with typhoon wind direction and entrance door opening angle as independent variables to build a typhoon flow model for a certain residential building, thus obtaining the pressure field of typhoon flow based on virtual experiments, followed by a comparison and analysis of the wind pressure distribution and load size on the entrance door surface under different working conditions so as to determine the main factors causing entrance door safety accidents. The results indicate that the wind load on the entrance door under typhoons is closely related to the wind direction, but not much related to the door opening angle; with a 20°wind direction of a typhoon, the maximum wind load thus obtained on the entrance door is likely to cause safety accidents.