The applicability evaluation of the engineering safety management capability system is an important prerequisite and condition for enhancing the level of intelligent safety management to improve the status quo of traditional engineering project safety management. Based on an analysis of the influencing factors of the applicability of the engineering safety management capability system, applicability evaluation system for the engineering safety management capability system is constructed at four levels: expected goals, framework rationality, content coordination, and operational effectiveness. Analytic hierarchy process (AHP), entropy weight method and subjective-objective combination weight method are used to determine the weight, while fuzzy comprehensive evaluation method is adopted to evaluate the applicability level of practical engineering projects. The results show that the system basically achieves the expected goal of intelligent, networked and collaborative engineering safety management during the actual operation of the engineering, thus providing practical reference for the promotion and application of the engineering safety management capability system.