Based on a comparative analysis of the advantages and disadvantages of several methods for calculating cable force, with the tied arch continuous beam of Donghai Bridge as a case study, an optimization model of suspender tension has thus been constructed by introducing the influence matrix method for the reduction of the number of suspender tensions. Meanwhile, a bridge model to verify the reliability of the optimized model has been established by using the finite element analysis software Midas Civil. The research results show that the introduction of influence matrix method effectively reduces the tensioning times of suspenders, thus reducing the tensioning adjustment times of suspenders to two times, with the difference between the bridge cable force of optimized suspenders and the design value controlled within ±3%, fully meeting the requirements of construction control.