Abstract::A tentative development and evaluation has been made of the axial force-bending moment interaction hysteresis model. Based on the principle of metal plasticity, the axial force-bending moment interaction hysteresis model (N-M model) has been developed, with its basic principle introduced. Combined with a frame model and a fiber model, an evaluation has been made of the effectiveness of the N-M model in predicting the structural nonlinear dynamic time history response, mode shape, global extreme value response and the effectiveness of the response under reversed cyclic loading. The results show that the predicted results of the N-M model, characterized with a high accuracy, are in good agreement with the measured earthquake damage records, thus providing a reasonable and efficient calculation way for the nonlinear analysis of structures.