Three identical reinforced concrete frame node models have been made by utilizing ANSYS finite element analysis software. A reversed low cycle loading has been made on the seismic capacity of frame nodes, under the control of vertical shaft pressure, with its axial compression ratios being 0.3, 0.5, 0.7. A research has thus been conducted on the seismic capacity of frame nodes, as well as the change regulation of crack development, ductility, and energy dissipation capacity. The results show that, to a certain extent, with the increase of frame column end shaft pressure, the restraint effect of concrete in the core area of frame nodes gradually increases, the shear deformation in the core region of the frame nodes is effectively limited, and the shear bearing capacity and energy dissipation ability is improved to some degree.