Combining with the means of solidity, conductivity and tensile properties measurement as well as microstructure observation, the welding wire preparation method of homogenization treatment-hot extrusion-drawing anneals-micro scraping was adopted to test the parameters for optimizing Al-Mg-Zr alloy welding wire production process, and Al-Mg-Zr alloy welding wire was successfully prepared. It shows that the welding wire of bright surface, good quality and excellent welding performance, which meet the requirement for actual use, can be obtained under the conditions of homogenization treatment at 470 ℃ for 24 hours, extrusion temperature at 420~430 ℃, extrusion ratio for 50~60 and intermediate anneals condition after drawing being 410 ℃/90 min.