The meaning of statistical process control and the control core tool-control charts are analyzed from the aspects of quality management development, the quality management in China's packaging industry and the necessity of applying statistical process control in packaging enterprises. On the basis of it, X-R control chart is used to analyze and monitor the packaging solvent residual quantity during the compound process. The on-site personnels can find the deficiencies in their own process quality control through detecting the correlative process fluctuation and the slow variation. In addition, SPC provides objective basis for quality management personnels to assess the quality of semi-products or products.