In view of the basic composition of the motion oxygen making equipment, the programme of control system about the mobile oxygen-making device is proposed and the control system hardware circuit and system's control software are also designed. Taking MCS-51 single chip computer as core part, and using fuzzy PID method to control the oxygen-making device compressor and molecular sieve electric motor, the system can measure and control the oxygen content in the specific situation and also keep it on the given value to achieve the specific functions. The results proved that the system has accurate measurement property and stable control of the oxygen content.