Both Adorno and Nietzsche handed over the mission of saving the survival plight of contemporary human beings to art,which is concerned with suffering, but their art-centered intervention ways and salvation methods are different. Nietzsche believes that art transcends suffering and truth with the appearance of beauty, releases the individual sensibility suppressed by reason, awakens the will of life, makes an aesthetic defense for the world and life, affirms the reasonableness of human existence, and gives people the hope of survival. Therefore, we should use art to break the shackles and redeem human nature. Adorno calls for the “negation essence” of art, emphasizes that art saves truthful content with aesthetic illusions and alienates society with its riddle-like aesthetic form. Therefore, it is necessary to realizes negative criticism of the externally alienated world through anti-art, thereby redeeming humanity. However, no matter Nietzsche’s affirmative transcendence or Adorno’s negative criticism, art has not obtained any substantial foundation existence except aesthetic illusion, which doomed their salvation road to be pale and utopian in the face of cruel social reality.