After entering the 20th century, especially after the two world wars, the US research universities have risen rapidly, and the national scientific and technological system led by the federal government and the talent training environment have gradually been formed and continuously optimized. At the same time, the United States has formed and perfected an open talent system. It opens the door for immigration, study and employment and absorbs the global scientific talents, constantly enjoying the tremendous benefits of international talent inflow, and gathering the largest group of world-class scientists not only born in America but also from other countries. America has become a world-recognized higher education center and technology center. The successful experience of the cultivation of scientific and technological talents and the absorption of foreign talents in the first half of the 20th century is of great reference and enlightenment to China’s scientific and technological development and talent training in the new era.