Based on the PSR model, a system of factors influencing the health of world natural heritage tourism landscape is constructed from three dimensions: pressure, state and response. DEMATEL method is used to identify these factors and analyze the comprehensive influence degree, cause degree and centrality of each influencing factor. The results show that：from the the perspetive of cause degree, there are eight causing factors influencing the health of the world natural heritage tourism landscape, such as population density, tourist number, landscape characteristics, etc. and eight resulting factors such as tourist capacity, economic development level, environmental law enforcement, etc. From the perspective of centrality, the centrality values of 8 factors including tourist capacity, economic development level, environmental law enforcement, and tourism income all exceed 2.5, which are the main factors affecting the health of the world natural heritage tourism landscape. Combining the four-quadrant method, according to the magnitude of the degree of cause and center, the factors influencing the health of the world natural heritage tourism landscape are divided into four types: high cause-high centrality factors, low cause-high centrality factors, high cause-low centrality factors and low cause-low centrality factors. High cause-high centrality factors, including three factors: tourist arrivals, population density, and landscape visibility, play a key role in the health of the world natural heritage tourism landscape. And corresponding management strategies were put forward according to different types.