Food packaging safety incidents occur frequently, which makes people’s sensitive attention to food safety extend to the safety of its outer packaging; with the arrival of 5G era, 5G’s outstanding technical advantages provide strong technical support for food packaging safety control. At present, RFID automatic identification technology, two-dimensional code technology and sensor technology have been successfully applied in the field of food intelligent control. The security upgrade of the intelligent management and control technology of food packaging life cycle in the 5G era can be realized from the establishment of a large database of food packaging safety management and control, the promotion of the Internet of Things, and 5G + intelligent packaging. The application of 5G technology to the intelligent management and control upgrade of the food packaging industry will help to create a highly intelligent, fully automatic, multi-interactive food packaging security management and control system, bring a new transformation and upgrade to the packaging industry, and realize the fission-type development of the Internet of Everything.