The “Spirit of the Red Boat” with the spirit of initiative, struggle and dedication as its main content is the strong spiritual strength and precious spiritual wealth nurtured by the Communist Party of China in the great cause of Party building. It has strong advanced nature and is an effective resource for ideological and political education in colleges and universities. Faced with the new situation and tasks of the new era, it is of great value to integrate the “Spirit of the Red Boat” into it. It can not only use the effective platform of efficient ideological and political education to open up new channels for its inheritance and promotion, but also promote the innovative development of ideological and political education in colleges and universities, and better cultivate the new generation of the times. In the process of integrating the “Spirit of the Red Boat” into the ideological and political education in colleges and universities, it will inevitably face many challenges from inside and outside. We must change with the times and circumstances, and innovate the path of integration. Firstly, we should do a good job of indoctrinating hard means into classroom teaching; Secondly, we should use the soft method of cultural education to integrate it into campus culture; Thirdly, we should use new media technology to integrate it into the new network channels; Finally, we should pay attention to the cultivation through practice and integrate it into extracurricular practice.