Based on the global principal component analysis (PCA), this paper constructs a comprehensive evaluation system for the quality of economic growth of in Hunan. Through the panel data from 1996 to 2014 in Hunan Province, this paper makes a comprehensive evaluation on the economic growth quality of the local cities in Hunan. The results show that: The economic development of different cities in Hunan province is not balanced, the quality level of economic growth varies greatly and the regional gap of the quality of economic growth is gradually widening. The quality of economic growth of the first gradient cities in Hunan, increased significantly and rapidly in the first 10 years of 21st Century. Taking the first gradient (Changsha, Zhuzhou, Xiangtan and Yueyang) as the leading cities, the main cities of second gradient (Chenzhou, Changde, Yiyang and Hengyang) as the sub core cities, the quality of economic growth in Hunan is gradually developing from the eastern cities to the central and western cities.