The integration of the “Internet plus” and the packaging industry has given rise to the O2O packaging design. As a new design model, O2O packaging design has the realtime, ondemand and alwaysonline characteristics, and therefore is helpful to solve the longstanding problems of the short service radius, the lack of design resources and the dissatisfaction of the personalized demand existing in the packaging enterprises. At present, the online service of O2O packaging design is faced with a situation where a variety of design patterns coexist in practice. While its offline service relies on cloud manufacturing and cloud printing technology to realize flexible production. In the future, the optimization of O2O packaging design process shall still depend on continuous technological innovation to provide development assistance, and at the same time, it is also necessary for packaging company to establish the network thinking, and make the process mature through the innovation of management mechanism and business thinking.