Waste in colleges and universities are produced in great number and at great speed, but it is not effectively dealt with. The effective treatment of waste affects the establishment of the standard of ecological civilization construction in our country. This paper attempts to build a multi level reduction model for campus waste from such three aspects as the source reduction, process reduction and terminal reduction. The source reduction includes the publicity of “meal culture” in the canteen area, the implementation of “access control + compensable garbage collecting area” at the dormitory area, the implementation of overall “plastic limitation” in the public area, and the enforcement of “equipment efficient use” in the teaching area. The process reduction includes the waste producers’ effective classification and effective sorting treatment of the waste. the terminal reduction includes the internal self disposal and external treatment of the campus waste. The establishment of the multi level reduction model makes the implementation of reverse logistics of colleges and universities more clear, smooth, efficient and universal.