Memetics is a newly-developed theory on the basis of Darwin's theory of evolution on the purpose of explaining the law of human culture evolution. It has great research potential as one of focuses in field of pragmatics research over the latest decade offering a wider perspective for the study of language and culture. As a kind of Chinese uniquely contemporary art form, comic sketches are plain, humorous, vivid and impressive in special forms of language communication which have always been enjoying high popularity among the audiences from all walks of life. From analyzing the variations of the language memes in dialogues of comic sketches and underlying the laughter-eliciting mechanism of verbal Humor, it aims at expanding the scope of researching linguistic memes and giving new enlightenment to appreciation and usage of comic language.