Qijin Shu is a special witchcraft which spreaded in Wuyue area in the late Eastern Han Dynasty. In the Six Dynasties, Qijin Shu underwent a great transformation.It started as an regional witchcraft of ethnic minorities and then penetrated to the Han society. After Ge Hong's emending, Qijin Shu turned into one type of traditional Xingqi shu, and has been incorporated into the categories of Taoism and Medicine. In Sui and Tang Dynasties, Qijin shu had been recognized by official medical institution and became one of the most important part of traditional Chinese medicine.