Based on the horizontal comparison of regional economic opening of Hunan province in 2009, the degree of economic openness is in great difference. The different resulted in unbalanced regional economic growth and restricted economic development of Hunan province. Some suggestions on how to improve the level of economic opening and to develop the balanced regional economic are listed,such as : understanding the comparative low total economic openness degree to develop potential positively; inducing and making full use of the foreign capital and the developed coastal areas in order to promote rapid economic development; using local resource superiority and following the market regulation to accelerate industrial structure adjustment; implementing strategies of “bringing in” and “going out” and combine them together as well.