Aiming at the failure problems such as blistering, yellowing, cold brittleness and loss of adhesion of acrylate pressure-sensitive adhesives for home appliance labels, through molecular design, a temperature-resistant and anti-aging solvent acrylate pressure-sensitive adhesive was prepared by free radical solution polymerization with acrylic acid-2-ethylhexyl ester (2-EHA) and butyl acrylate (BA) as the soft monomers, methyl acrylate (MA) and vinyl acetate (VAc) as the hard monomers, acrylic acid (AA) and urethane acrylate (WAM-X) as the functional monomers, ethyl acetate as the solvent, and benzoyl peroxide (BPO) as initiator, with the addition of crosslinking agent and antioxidants. The effects of feeding process, monomer ratio, initiator and crosslinking agent dosage on the adhesive properties of the pressure-sensitive adhesive were investigated, and the effects of antioxidant on the yellowing and aging resistant properties of the pressure-sensitive adhesive were also studied. The viscoelasticity and transmittance of the pressure-sensitive adhesives were determined by rheometer and visible spectrophotometer, respectively. The results showed that when the mass fraction of soft and hard monomers was 90% (the mass ratio of soft and hard monomers was 10:1), the mass ratios of BA to 2-EHA and MA to VAc were both 1:1, the mass fractions of functional monomers AA and WAM-X were 9.8% and 0.2%, respectively, the amount of initiator was 0.5% of the total monomer mass, and the amounts of aluminum acetylacetonate and antioxidant Deox S80 were 0.5% and 0.15% of the total monomer mass, respectively, the prepared pressure-sensitive adhesives showed excellent comprehensive performance. The initial adhesion at room temperature was that of 11# steel ball, peel strength was more than 25 N/25 mm, and the holding time exceeded 100 h. It kept the holding adhesion for more than 24 h at 80 ℃without slippage. Moreover, after alternating between hot and cold, no yellowing and cold brittleness occurred, showing good anti-aging performance and meeting the harsh working conditions required for home appliance labeling.