Grand polystyrene beads (GPO) blended foam is a new type of cushioning packaging material. Taking GPO as the research object, the static compression test was carried out. The experimental data were processed by MATLAB software, and the stress-strain curve and buffer coefficient maximum stress curve were obtained. Based on the minimum buffer coefficient and maximum stress, the buffer pad design of a lithium-ion battery product was carried out, while the design schemes of several buffer materials were compared. The results show that GPO foam material has the best cushioning performance in the stress range of 230~320 kPa, and the minimum cushioning coefficient is about 2.6. GPO material is suitable for the cushioning packaging of heavy products. The research is of great significance to the rational use of storage and transportation space, as well as the improvement in logistics packaging scheme.