Aiming at the problem that the movement of the knife axis and the film axis, the material axis and the film axis appear to be out of synchronisation which affects the quality of packaging when the three axes of pillow packaging machine are controlled in coordination, the pillow packaging machine control system based on the double electronic cam algorithm is designed with the self-developed motion controller (Motion-Control-V-3.3) as the control core. According to the cam movement law, the mathematical model is established and the 5th polynomial electronic cam curve is optimised to solve the problem of coordinated synchronization of three axes, namely the film axis, material axis and knife axis. At the same time, the three-axis zero position is periodically compensated to make up for the influence of mechanical error. The experimental results show that the system error is between ±0.5 mm and there is no breakage of packaged products when processing films with a film length of 80~320 mm and a working speed of less than 120 packages/min (line speed of about 9600 mm/min). This double cam control system is effective and feasible.