In order to improve the evaluation system of elderly adaptive design for drug packaging，a quantitative evaluation system is constructed using user survey and analytic hierarchy process, and the feasibility of the system is verified through specific design cases. The evaluation system consists of 3 primary indicators and 9 secondary indicators. The research results indicate that in the proposed evaluation system of elderly adaptive design for drug packaging, the primary indicators of visual design have the greatest impact and the highest weight. In the secondary indicators, the reasonable use of fonts in visual design, ease of opening in functional design, and safety in psychological attributes have the greatest impact and highest weight. Standardizing and quantifying the elderly design of drug packaging can further promote the development of elderly design for drug packaging and clarify the direction of drug packaging.