The structural variability of paper packaging is a design method that makes use of the preset structure of packaging to carry out modification design, so that the packaging can be reused. On the basis of summarizing the basic design methods such as pre pasting, pre folding and pre die cutting, the main design directions for realizing the variability of functional structure are put forward, including the integration of packaging products, the generalization of packaging modification and the creation of packaging entertainment culture, which could provide useful design reference and development ideas for the sustainable design of the structure of paper packaging containers.