The assembly efficiency of take-out packaging in catering business has an important impact on the operating efficiency of enterprises. Some representative discs and tube cartons were selected from the market, with the drawing models and experimental samples established, simulated assembly experiments carried out, the assembly time of the cartons obtained for the analysis of these data. The results showed that complex structures such as handle dual-purpose structure, hook and lock showed obvious assembly difficulties and low assembly efficiency in the assembly process. The machine preformed stackable structure can reduce the overall assembly time and significantly improve the assembly efficiency. Based on the in-depth study of the above laws, the packaging structure of carton was modified, and the feasibility of the modified scheme was investigated through experiments. The results showed that when designing the packaging structure of western food take-out cartons, the integrated lining box type and the machine preformed stacking structure box type should be preferred, and the design of split lining and complex structure lining should be avoided.