In order to solve the problems such as sluggish electron transfer, severe concentration polarization and poor cycling performance of V2O5, Na0.4V2O5 nano-powder materials was prepared by one-step hydrothermal method and used as cathode material of zinc-ion battery. The results reveal that the rate performance and cycle stability of Na0.4V2O5 electrode are better than those of V2O5 electrode. Na+-doped can change the layered structure of V2O5 and effectively improve the electron transport and ion diffusion in the solid electrode. Thus, Na0.4V2O5 improves the conductivity characteristics and structural stability and is a promising electrode material with excellent rate performance and cycle stability.