Spray-forming Al-Cu-Mg alloy was compressed to 60% deformation at the temperature ranging from 300 ℃ to 450 ℃and strain rates in the range of 0.01~10.00 s-1 on a Gleeble-3180 thermal simulation machine. The results showed that the flow stress decreased with increasing deformation temperature and increased with increasing strain rate in the hot compression deformation of spray formed Al-Cu-Mg alloy. Constitutive equation and parameter Z were established to describe the deformation behavior of the alloy at high temperature, and the Q value was 158.52 kJ/mol. 3D power dissipation and processing maps were analyzed under strain values of 0.4 and 0.8. When the strain was increased from 0.4 to 0.8, the processing performance changed remarkably. The region in 320~370 ℃ and 6.68~10.00 s-1 exhibited an improved processing performance.