During electrochemical machining process, it is difficult to control the shape of the machined surface of anisotropic alloy materials. Therefore, the position function was used to establish the micro-material model for two-phase Ti-48Al-2Cr-2Nb alloy, and then the electrochemical machining simulation micro-physical model was set up. The influences of the macro-process parameters on the evolution behavior of surface micro-morphology were investigated. The results showed that when the electrolyte flow rate and feed rate were in the range of 14.7~23.4 m/s and 1.7~2.3 mm/min respectively, the roughness Ry of the machined surface decreased with the increase in the flow rate and feed rate. The smoothest surface (Ry=0.677 μm) was obtained under the condition of the voltage being 21 V, the feed rate 2.3 mm/min and the electrolyte flow rate 23.4 m/s. The simulation of micro-morphology evolution showed that the most polished surface had undergone a process of roughening and polishing.