The rutile titanium dioxide was coated with Zr-PEG600 to improve its application performance. By means of orthogonal test method, the effects of the stirring speed, the dosage of SHMP, ZrOCl and PEG600 on titanium dioxide in the performance were explored. The Zeta potential of rutile titanium dioxide was examined by Nano-zs potential instrument, and the surface effect of rutile titanium dioxide was observed by scanning electron microscopy(SEM), transmission electron microscopy(TEM) and settlement test. The result showed that stirring speed of 300 r/min, 1.0% dispersant，2% ZrOCl, 0.005 mol/(100 g TiO2) PEG600 achieved the optimal process.