With the aim to meet the demand of color reproduction technology in the design and manufacture of packaging products in the modern packaging industry chain, by means of establishing a color reference platform from packaging design，packaging manufacturing to packaging application, an integrated soft-copy and hard-copy model named “4-process color plus spot color printing” with the application solution was proposed for processing printing and spot-color printing with high fidelity. The test results showed that: 1) after twice color matching of the IT8.7-3 sample, the average color difference was reduced to 2.50 and E less than 3.00 was as high as 95.68%; 2) after the color matching and optimization algorithm being processed, the sample color block and the image approached the target requirement, with the image visual effect being consistent. The algorithm could meet the precision requirements of industrial production and achieve consistency in packaging design and product cross-media color reproduction.