There is a wide variety of sources of transglutaminase, such as from microorganisms, animals and plants. It is widely used in the application in food, textile, pharmaceutical, leather and other fields. The impact of transglutaminase on the properties of plant protein biological packaging films of soybean protein isolate film, wheat gluten film, peanut protein isolate film, corn protein film and animal protein biological packaging films of gelatin film, whey protein film is reviewed. The study on the composite of protein biological packaging film with other materials is the trend of biodegradable film research in future.