The research progress is reviewed on the chemical modification of epoxy resin with organic silicon in four aspects of silicone oil modified epoxy resin, silane coupling agent modified epoxy resin, silicone modified epoxy resin and silastic modified epoxy resin. Direction of research on organic silicon-modified epoxy resin is presented considering the high performance of polymer modified materials. Previous studies show that silicon-modified epoxy resin is developing in the direction of silicon-modified epoxy resin containing new function group and structure.