A novel UV photoluminescence security ink was synthesized. The characterization such as the size (19.5μm), stickiness (6.85), viscosity (93.77p), friction resistance (over the 500 frequency) of the sample were detected. The templates such as lines, gray scale, text, graphics and images were designed and further made into printed plate to perform screen printing. The results show that the ink suits the hectograph well. An imprint can dry quickly under the shine from an UV illuminant and radiate a yellow and green light after their shine from white light.