By adopting the polymerization degree 1 067 broad-leaved pulp as raw material, LiCl/DMAc as the solvent, the cast films with oxygen permeation flux (OPF) and water vapor permeability (WVP) are prepared by scraping. The research sets up the mathematical model of the dissolved process parameters and OPF and WVP coefficient of cellulose membrane. The results show that the OPF and WVP coefficient first increases and then decreases after the extension of activation time and dissolution temperature, and the standing time led to reduce the OPF and WVP coefficient. Through calculating on the regression equation, the dissolution conditions about OPF and WVP indicate a secondary association.