To promote the marketization implementation of senile design in drug packaging, based on the entire process of packaging design implementation and combined with the specific needs of senile design, the relevant issues are conducted on the implementation path of senile design in drug packaging. The constitute and characteristics of the implementation path of senile design in drug packaging were analyzed, which indicated excellent senile drug packaging should not only be limited to the design process, but also have good compatibility in all aspects of the circulation process in order to establish an effective implementation path and enter the market. On the basis of implementing the principles of path design, the key points for constructing the implementation path of senile design in drug packaging were analyzed, as well as the composition of the corresponding evaluation and optimization system. The research on the implementation path of senile design in drug packaging helps to comprehensively grasp the key points of drug packaging design for the elderly, making the designed products easy to market.