In recent years, the detection of organophosphorus pesticides based on non-enzymatic nano electrochemical sensor has attracted much attention. It has the advantages of low detection cost, convenient operation, high sensitivity and fast response. The appearance of carbon nano-materials, nano-metal particles, nano-metal oxides and nano-conducting polymers and their composites greatly improved the performance of organophosphorus pesticide electrochemical sensors. With the emergence of nanotechnology, some progress in synthesizing analyte-specific nanomaterials has been made, which can be used to construct highly specific, strongly selective, and cost-effective electrochemical sensors to replace other analytical technologies. In view of the importance of the new structure of nanomaterials, the latest research progress in the field of non-enzymatic nano electrochemical sensor is reviewed, with the synthesis of nano-composites and methods for detecting organophosphorus pesticides highlighted.