To modify polyamide 6, hyperbranched polyether epoxy (AHEP) with combination of aliphatic moieties was incorporated at different concentrations into polyamide 6 resin. The melt flow behavior, crystallization behavior, and mechanical properties of the AHEP-PA6 blends were investigated by using melt flow indexer, WAXD, mechanics universal texter and SEM. The results showed that the degree of crystallinity was improved to certain degree with the addition of AHEP. The crystal form of PA6 changed into more stable α-form crystal, with the weakening of γ-form. AHEP could be uniformly dispersed in PA6 matrix. The strong interaction between the two and the microcrosslinking structure improved the mechanical properties of PA6, and the fracture apperance of the blend system presented the characteristics of in-situ toughening and strengthening.