Abstract:Ta2O5/Ta2O5/Ta2O5-TiO2/TiO2/Ti multilayer composite coating doped or undoped with Ag was developed on the surface of Ti6Al4V alloy by magnetron sputtering (denoted as Ag-MTa2O5 and MTa2O5). The coating samples were characterized and detected by SEM, XRD, EDS, nano-indentation instrument, electrochemical workstation and plate counting method. The results showed that the doping of Ag played an important role in the structure and properties of the MTa2O5 multilayer coating. Compared with the MTa2O5 coating, Ag-MTa2O5 coating exhibited larger grain, lower density, slightly lower mechanical properties and corrosion resistance, while showing excellent antibacterial property with an antibacterial rate of 100%.