In view of real-time monitoring of temperature and humidity data of cold chain incubator and the requirements of Good Supplying Practice issued by China Food and Drug Administration, the wireless temperature and humidity monitoring system composed of wireless temperature and humidity monitor and cold chain monitoring cloud platform was developed. The wireless temperature and humidity monitor could collect real-time data of cold chain incubator, and transmit data to the cloud server through the GPRS network. The users could view real-time temperature and humidity data and geography information through cold chain monitoring cloud platform. The accuracy of temperature and humidity data collected by the system was ±0.3 ℃ and ±3% respectively, and the stability of wireless transmission was reliable. The system could be used in the cold chain packaging field of food and drug.