A high performance liquid chromatography (HPLC) for analysis of 2 antioxidants and 2 light stabilizers in polyethylene-silver nanocomposites was developed. The film was dissolved with toluene, and cleaned with centrifugal. Then the solution was filtered through nitrogen blowing before analyzed through HPLC. The separation was performed on XBridgeTM C18, while methanol was used as the mobile phase and quantified by external standard method. The results indicated that the method had good linear relationships with coefficient r2>0.998 9. The average recoveries of the 4 additives were in the range of 81.6%~101.8%, and the relative standard deviations were in the range of 1.4%~9.1%. The limits of detection (LODs) were 0.03~0.30 μg/mL and the limits of quantification(LOQ) were 0.10~1.00 μg/mL.