The causes of the phenomenon of “water mist” on the surface of printing products were analyzed by taking the “Hongqiqu box” cigarette products as an example, while the effect of shrink packaging sealing technology on the formation of “water mist” on the surface of printing products was studied. Experimental results showed that factors of coating thickness, drying degree and stirring of the waterproof varnishing could affect the formation of “water mist”. Its formation is less likely with thinner thickness of waterproof varnishing coating, the greater UV lamp power and the slower drying rate. In order to reduce the “water mist” phenomenon, the paper should be carried out for conditioning and tested against moisture before the production, the waterproof varnishing should be mixed evenly, while the roller of varnishing coating’s weight, UV lamp power, and the rate of machine should be controlled in the production to achieve stable quality control.