The better condition for synthesizing organic silicon resin is selected through experiments. The modified silicone resin is obtained by blending polyurethane with silicone resin. The optimal condition for preparing modified silicone bamboo base materials is studied by applying the modified organic silicone resin to the surface coating of bamboo base materials. Results show that the optimal condition for the synthesis of organic silicon resin is as follows: phenyl 3 armour oxygen radicals silane and methyl dimethoxy silane for the synthesis of monomer, with the volume of the two monomer ratio of 1.5, hydrolysis temperature of 55 ℃, hydrolysis time of 2.5 h, HCl/Si—OR，H2O/Si—OR，water, xylene, acetone, the quality of the ratio respectively at 0.002 00, 10/3 and 8:4:1; Best preparation condition of modified silicone of bamboo base materials is the added quality score of polyurethane and siloxane accounting for 12.5% of the resin total mass, dosage of curing agent is 24.5% of the total quality of resin, and baking for 3 h at 80 ℃ condition; IR spectra shows that organic silicon resin has wide —Si—O—Si—absorption peak; Resistance to chemical corrosion test results show that the synthesis of organic silicone modified resin paint film has good resistance to chemical corrosion.