By using the geographical detector and by adopting ArcGIS spatial analysis method, based on the data issued by the cultural and tourism administration network, statistical yearbook and geospatial data cloud, an analysis has been made of the influencing factors of spatial diversity of tourism scenic spots in Henan Province. The results show that the spatial distribution of tourist attractions in Henan Province gradually evolves from southwest-northeast to northwest-southeast developing trend, while the center of gravity of the spatial distribution of tourist attractions gradually shifts from north to south. The influence of social factors on tourism spatial distribution keeps fluctuating; meanwhile, the influence of economic factors on tourism spatial distribution shows a continuous increasing trend, with the influence of natural factors characterized with a relatively small fluctuation.