Based on the construction of a comprehensive evaluation index system of agricultural ecological?economic system in Hunan Province, with the entropy method and coupling coordination model combined together, an analysis has been made of the comprehensive development level and coupling coordination degree of agricultural ecological-economic system in Hunan Province from 2004 to 2018. The results show that from 2004 to 2018, the comprehensive development level of agricultural ecosystem and agricultural economic system in Hunan Province showed a fluctuating upward trend; during the study period, C-value of the coupling degree of agricultural ecological?economic system in Hunan Province was higher than 0.9, which was in a highly coupling state, with the optimal coupling state reached in 2018; during the study period, D-value of the coupling coordination degree of agricultural ecological-economic system in Hunan Province kept fluctuating, rising from 0.620 to 0.827, i.e., from the initial primary coordination degree to good coordination degree. According to the inertial development trend, the coupling coordination degree of agricultural ecological-economic system in Hunan Province is expected to reach the high-quality coordination degree in the future.