ER5356 aluminum alloy welding wire, prepared by adopting continuous extrusion drawing, scraping, and brightening technology, is to be used for MIG welding of annealed 5083 aluminum alloy, followed by a series of tests and analyses of the welding joints by means of metallographic examination, scanning, hardness and tensile tests. The experimental results show that the welding effects of the wires thus prepared are satisfactory, without such defects as cracks, inclusions, etc. The micro-structure of the welded joints is well distributed, with 68 HV the minimum hardness of welding seam center, with 277 MPa the tensile strength of welded joints , and 92.3% its strength coefficient, thus exhibiting such an excellent mechanical performance that it fully meets the actual welding requirement and ship usage requirement.