In view of the fact that the current highway infrastructure development forecast is basically a virgin ground, based on the gathered information of the historical development of the highway infrastructure construction in China, a detailed analysis has been made of its developmental features and a tentative analysis of its causes as well. A grey prediction model has been established and a grey prediction program has been worked out, followed by a future development trend prediction of the highway infrastructure construction in China, based on the correlation test, the posterior variance test and the residual test. The research and forecast results show that the proposed grey forecasting model is of high precision, and the formulated grey prediction program has achieved a good effect, with a great potential for the future development of the highway infrastructure construction and the structural readjustment. The prediction results can be referred to by the highway traffic management department for the development planning and decision making.